Description

1-(1-Methyl-4-(Thiophen-3-Yl)Piperidin-4-Yl)Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperidine-thiophene hybrid structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates targeting neurological receptors.
• Medicinal Chemistry Research: Serves as a key scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and process development stages for creating new therapeutic molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the pharmaceutical industry.
• Chemical Reference Standard: Can be utilized as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	1-(1-Methyl-4-(Thiophen-3-Yl)Piperidin-4-Yl)Ethanone
CAS No.	514181-52-3
Molecular Formula	C12H17NOS
Molecular Weight	223.33 g/mol
Synonyms	1-[1-Methyl-4-(thiophen-3-yl)piperidin-4-yl]ethanone; 1-(1-Methyl-4-(3-thienyl)-4-piperidinyl)ethanone; 1-(1-Methyl-4-(thiophen-3-yl)piperidin-4-yl)ethan-1-one; 4-Acetyl-1-methyl-4-(3-thienyl)piperidine; 514181-52-3; Ethanone, 1-[1-methyl-4-(3-thienyl)-4-piperidinyl]-
EINECS	Contact for details

Quality Control

Our 1-(1-Methyl-4-(Thiophen-3-Yl)Piperidin-4-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.