Description

6-Methyl-3-(Piperidin-1-Ylcarbonyl)-4,5,6,7-Tetrahydro-1-Benzothien-2-Ylamine is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. Research and development teams in the global pharmaceutical and biotechnology sectors require this material for its precise chemical functionality to enable efficient and scalable synthetic routes.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates targeting neurological disorders.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• API Synthesis: Serves as a core scaffold or a key fragment in the construction of complex molecules intended for clinical development.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Chemical Reference Standard: Utilized as an analytical standard for quality control and method validation in API manufacturing.
• Academic Research: Employed in university and institutional labs for exploratory research in organic synthesis and pharmacology.

Basic Information

Product Name	6-Methyl-3-(Piperidin-1-Ylcarbonyl)-4,5,6,7-Tetrahydro-1-Benzothien-2-Ylamine
CAS No.	512826-70-9
Molecular Formula	C16H24N2OS
Molecular Weight	292.44 g/mol
Synonyms	6-Methyl-3-(1-piperidinecarbonyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine; 2-Amino-6-methyl-4,5,6,7-tetrahydro-3-(1-piperidylcarbonyl)benzo[b]thiophene; 4,5,6,7-Tetrahydro-6-methyl-3-(1-piperidinylcarbonyl)-1-benzothien-2-amine; 512826-70-9; 6-Methyl-3-(piperidine-1-carbonyl)-4,5,6,7-tetrahydrobenzo[b]thiophen-2-amine
EINECS	Contact for details

Quality Control

Our 6-Methyl-3-(Piperidin-1-Ylcarbonyl)-4,5,6,7-Tetrahydro-1-Benzothien-2-Ylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring the material is suitable for demanding pharmaceutical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.