Description

4-Bromo-1-(2-Fluoro-Benzyl)-3-Nitro-1H-Pyrazole is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated and nitrated pyrazole core enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo, fluoro, and nitro functionalities into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Serves as a precursor in the development of new generation herbicides, fungicides, and insecticides, leveraging its halogenated pyrazole structure.
• Material Science: Used in the research and synthesis of advanced organic materials, including liquid crystals and organic semiconductors.
• Chemical Biology: Employed as a probe or labeling agent in biochemical research due to its reactive bromo and nitro groups.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Bromo-1-(2-Fluoro-Benzyl)-3-Nitro-1H-Pyrazole
CAS No.	512823-86-8
Molecular Formula	C₁₀H₇BrFN₃O₂
Molecular Weight	300.09 g/mol
Synonyms	4-Bromo-1-[(2-fluorophenyl)methyl]-3-nitro-1H-pyrazole; 1-(2-Fluorobenzyl)-4-bromo-3-nitropyrazole; 4-Bromo-1-(2-fluorobenzyl)-3-nitropyrazole; 4-Bromo-3-nitro-1-(2-fluorobenzyl)-1H-pyrazole; Pyrazole, 4-bromo-1-[(2-fluorophenyl)methyl]-3-nitro-; CAS 512823-86-8
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-(2-Fluoro-Benzyl)-3-Nitro-1H-Pyrazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply chain transparency and batch-to-batch reproducibility meets the stringent requirements of research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.