Description

Bicyclo[3.1.0]Hexane-2-Methanol, 4-Amino-, (1R,2S,4R,5S)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic amino alcohol building block of significant interest in advanced organic synthesis. This compound matters because its unique, rigid molecular framework and functional group arrangement make it a valuable chiral scaffold for constructing complex molecules with precise three-dimensional control. Pharmaceutical and agrochemical R&D teams need it for developing novel active ingredients, particularly as a key intermediate in the synthesis of potential drug candidates and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral targets.
• Agrochemical Synthesis: Used in the design and synthesis of novel, stereospecific pesticides and herbicides where the rigid bicyclic structure can influence biological activity and selectivity.
• Asymmetric Catalysis: Employed as a precursor or ligand in the development of chiral catalysts for enantioselective synthesis, leveraging its defined stereocenters.
• Fine Chemical Production: Acts as a specialized intermediate in the multi-step synthesis of complex fragrance molecules, dyes, and other high-value specialty chemicals.
• Academic & Industrial Research: Utilized in medicinal chemistry programs and methodological studies to explore new chemical space and reaction pathways involving strained ring systems.
• Peptidomimetics & Bioisosteres: Its structure is valuable for creating conformationally restricted analogs of peptides in drug discovery efforts.

Basic Information

Product Name	Bicyclo[3.1.0]Hexane-2-Methanol, 4-Amino-, (1R,2S,4R,5S)-Rel- (9Ci)
CAS No.	512790-53-3
Molecular Formula	C8H15NO
Molecular Weight	141.21 g/mol
Synonyms	rel-(1R,2S,4R,5S)-4-Aminobicyclo[3.1.0]hexane-2-methanol; 4-Amino-2-(hydroxymethyl)bicyclo[3.1.0]hexane (stereoisomer); Bicyclo[3.1.0]hexane-2-methanol, 4-amino-, (1R,2S,4R,5S)-rel-; (1R,2S,4R,5S)-rel-4-Aminobicyclo[3.1.0]hexane-2-methanol; Amino Bicyclohexane Methanol Derivative; Chiral Bicyclic Amino Alcohol; Bicyclo[3.1.0]hexane amino methanol building block.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) are available upon request, detailing specifications such as assay (by HPLC), chiral purity, and impurity profiles. We adhere to cGMP principles for production where applicable to support our clients in regulated development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.