Description

3-(3,4-Dihydro-2(1H)-Isoquinolinyl)-1-(3-Methoxyphenyl)-2,5-Pyrrolidinedione is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and psychiatric disorders. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new therapeutic agents. Consistent quality and reliable supply are paramount for ensuring the integrity of downstream drug development pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of proprietary drug candidates, especially within central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with targeted biological activity.
• Contract Manufacturing: Supplied to CDMOs for the scale-up and cGMP production of clinical trial materials and commercial APIs.
• Biochemical Research: Employed as a tool compound in pharmacological assays to study specific enzyme inhibition or receptor modulation.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	3-(3,4-Dihydro-2(1H)-Isoquinolinyl)-1-(3-Methoxyphenyl)-2,5-Pyrrolidinedione
CAS No.	511515-44-9
Molecular Formula	C20H20N2O3
Molecular Weight	336.39 g/mol
Synonyms	1-(3-Methoxyphenyl)-3-(3,4-dihydro-1H-isoquinolin-2-yl)pyrrolidine-2,5-dione; 2,5-Pyrrolidinedione, 3-(3,4-dihydro-2(1H)-isoquinolinyl)-1-(3-methoxyphenyl)-; UNII-9F8Q2R8W1N; 9F8Q2R8W1N; 3-(1,2,3,4-Tetrahydroisoquinolin-2-yl)-1-(3-methoxyphenyl)pyrrolidine-2,5-dione
EINECS	Contact for details

Quality Control

Our 3-(3,4-Dihydro-2(1H)-Isoquinolinyl)-1-(3-Methoxyphenyl)-2,5-Pyrrolidinedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.