Description

3-(3,4-Dihydroisoquinolin-2(1H)-Yl)-1-(2,5-Dimethylphenyl)Pyrrolidine-2,5-Dione is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and psychiatric disorders. It is essential for research and development chemists, process development scientists, and manufacturers in the pharmaceutical and biotechnology industries seeking to develop next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent drug candidates, especially for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new bioactive molecules.
• Process Chemistry & Scale-Up: Serves as a defined starting material or intermediate for kilogram-to-ton scale GMP manufacturing of APIs.
• Biochemical Tool Compound: Potential use in pharmacological assays and as a probe for studying specific enzyme or receptor interactions in academic and industrial R&D.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3-(3,4-Dihydroisoquinolin-2(1H)-Yl)-1-(2,5-Dimethylphenyl)Pyrrolidine-2,5-Dione
CAS No.	511515-43-8
Molecular Formula	C21H20N2O2
Molecular Weight	332.40 g/mol
Synonyms	1-(2,5-Dimethylphenyl)-3-(3,4-dihydro-1H-isoquinolin-2-yl)pyrrolidine-2,5-dione; 3-(3,4-Dihydro-1H-isoquinolin-2-yl)-1-(2,5-dimethylphenyl)pyrrolidine-2,5-dione; 2,5-Pyrrolidinedione, 3-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(2,5-dimethylphenyl)-; CAS 511515-43-8
EINECS	Contact for details

Quality Control

Our 3-(3,4-Dihydroisoquinolin-2(1H)-Yl)-1-(2,5-Dimethylphenyl)Pyrrolidine-2,5-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.