Description

A-D-Erythro-Pentofuranosyl Chloride, 2-Deoxy-, Dibenzoate (9Ci) is a protected glycosyl donor intermediate of significant importance in synthetic organic chemistry. This compound is a key building block for the controlled synthesis of nucleosides, nucleotides, and complex carbohydrate derivatives. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral agents, anticancer drugs, and other bioactive molecules where precise stereochemistry is critical. The CAS number for this compound is 503625-15-8.

Application

• Nucleoside/Nucleotide Synthesis: A critical glycosyl donor for the stereoselective construction of 2'-deoxyribonucleoside scaffolds, which are the backbone of DNA and many therapeutic agents.
• Antiviral Drug Research: Used in the development of prodrugs and active pharmaceutical ingredients (APIs) targeting viruses such as HIV, hepatitis, and herpes.
• Anticancer Agent Development: Serves as a precursor for modified nucleosides used in chemotherapy and targeted cancer therapies.
• Carbohydrate Chemistry: Employed in the synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics for biological studies and drug discovery.
• Process Chemistry & Scale-up: Used in pilot plants and manufacturing for the scalable production of high-value fine chemicals and pharmaceutical intermediates.
• Biochemical Research: Acts as a tool compound for studying enzyme mechanisms, such as those of glycosyltransferases, and for probing biological pathways.

Basic Information

Product Name	A-D-Erythro-Pentofuranosyl Chloride, 2-Deoxy-, Dibenzoate (9Ci)
CAS No.	503625-15-8
Molecular Formula	C19H17ClO5
Molecular Weight	360.79 g/mol
Synonyms	2-Deoxy-3,5-di-O-benzoyl-D-erythro-pentofuranosyl chloride; 3,5-Di-O-benzoyl-2-deoxy-D-erythro-pentofuranosyl chloride; 1-Chloro-2-deoxy-3,5-di-O-benzoyl-D-erythro-pentofuranose; 2-Deoxy-3,5-di-O-benzoyl-α-D-erythro-pentofuranosyl chloride; D-erythro-Pentofuranosyl chloride, 2-deoxy-, dibenzoate (9CI)
EINECS	Contact for details

Quality Control

Every batch of A-D-Erythro-Pentofuranosyl Chloride, 2-Deoxy-, Dibenzoate (9Ci) is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant techniques is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.