Description

2-Oxabicyclo[3.1.0]Hex-3-Ene-6-Carboxylicacid,Methylester,(1S,5S,6S)- is a high-purity, stereochemically defined bicyclic lactone derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique strained ring structure and defined stereochemistry make it an invaluable intermediate for constructing complex molecular architectures with high precision. This compound is primarily sought after by research and development laboratories and production facilities in the pharmaceutical and agrochemical sectors for the synthesis of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new asymmetric catalytic reactions.
• Material Science Precursor: Serves as a starting material for synthesizing specialized polymers or functional materials with unique properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including ring-opening and cycloaddition reactions.

Basic Information

Item	Details
Product Name	2-Oxabicyclo[3.1.0]Hex-3-Ene-6-Carboxylicacid,Methylester,(1S,5S,6S)-
CAS No.	503605-17-2
Molecular Formula	C8H10O3
Molecular Weight	154.16 g/mol
Synonyms	(1S,5S,6S)-2-Oxabicyclo[3.1.0]hex-3-ene-6-carboxylic acid methyl ester; (1S,5S,6S)-Methyl 2-oxabicyclo[3.1.0]hex-3-ene-6-carboxylate; (-)-Methyl (1S,5S,6S)-2-oxabicyclo[3.1.0]hex-3-ene-6-carboxylate; Bicyclic Lactone Ester; Chiral Oxabicyclohexene Ester; 503605-17-2; (1S,5S,6S)-Oxabicyclohexene Carboxylate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Quality is verified through a suite of analytical techniques including HPLC, GC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, it is recommended to keep the material at 2-8°C under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.