Description

3-Isoquinolinecarboxylic Acid, 6-[3-Chloro-2-(2H-Tetrazol-5-Yl)Phenoxy]Decahydro-, Hydrochloride (1:1), (3S,4As,6S,8Ar)- is a high-purity, complex heterocyclic compound with significant potential in advanced pharmaceutical research and development. Its intricate molecular architecture, featuring fused isoquinoline and tetrazole rings, makes it a valuable pharmacophore and key synthetic intermediate for creating novel bioactive molecules. This compound is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, especially for central nervous system (CNS) and cardiovascular targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Tool Compound: Potential application as a ligand or inhibitor in biochemical assays to study specific enzyme or receptor functions.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to construct complex molecules for agrochemical or material science applications.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	3-Isoquinolinecarboxylic Acid, 6-[3-Chloro-2-(2H-Tetrazol-5-Yl)Phenoxy]Decahydro-, Hydrochloride (1:1), (3S,4As,6S,8Ar)-
CAS No.	503290-66-2
Molecular Formula	C19H22ClN5O3 • HCl
Molecular Weight	440.77 g/mol
Synonyms	(3S,4aS,6S,8aR)-6-[3-Chloro-2-(2H-tetrazol-5-yl)phenoxy]decahydroisoquinoline-3-carboxylic acid hydrochloride; Decahydro-6-[3-chloro-2-(2H-tetrazol-5-yl)phenoxy]-3-isoquinolinecarboxylic acid, hydrochloride, (3S,4aS,6S,8aR)-; 503290-66-2; UNII-9K8T8V6A6T; 9K8T8V6A6T; 6-[3-Chloro-2-(1H-tetrazol-5-yl)phenoxy]decahydro-(3S,4aS,6S,8aR)-isoquinoline-3-carboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Isoquinolinecarboxylic Acid derivative is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and protected from light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm
Assay (on anhydrous basis)	98.0% - 102.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.