Description

Vilanterol Trifenatate CAS NO 503070-58-4 is a high-purity active pharmaceutical ingredient (API) belonging to the class of long-acting beta2-adrenergic agonists (LABAs). This compound is of critical importance for the development of advanced respiratory therapies, offering sustained bronchodilation. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the formulation of inhalation products for the management of chronic obstructive pulmonary disease (COPD) and asthma.

Application

• Active Pharmaceutical Ingredient (API) in combination dry powder inhalers (DPIs) for chronic respiratory conditions.
• Key component in fixed-dose combination therapies, often paired with corticosteroid APIs.
• Research and development of novel inhalation delivery systems and formulations.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Process development and scale-up studies for generic pharmaceutical manufacturing.
• Pharmacological studies investigating long-acting beta2-adrenergic receptor activity.

Basic Information

Product Name	Vilanterol Trifenatate
CAS No.	503070-58-4
Molecular Formula	C24H33ClN3O7S
Molecular Weight	543.05 g/mol
Synonyms	Vilanterol Trifenatate; Vilanterol triphenylacetate; GSK642444; GSK 642444; 4-{(1R)-2-[(6-{2-[(2,6-Dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol triphenylacetate; (R)-4-(2-((6-(2-((2,6-Dichlorobenzyl)oxy)ethoxy)hexyl)amino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol triphenylacetate
EINECS	Contact for details

Quality Control

Our Vilanterol Trifenatate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity determination, and residual solvent analysis, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting regulatory submissions and ensuring supply chain integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.