Description

5-Isoquinolinamine,5,6,7,8-Tetrahydro-,(5S)-(9Ci) is a chiral, saturated isoquinoline derivative, a high-value building block in advanced organic synthesis. Its defined stereochemistry and amine functionality make it a critical intermediate for constructing complex molecules with specific biological activity. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and catalyst development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the specific stereochemistry can influence biological efficacy and environmental profile.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals, dyes, and advanced materials requiring a saturated isoquinoline scaffold.

Basic Information

Product Name	5-Isoquinolinamine,5,6,7,8-Tetrahydro-,(5S)-(9Ci)
CAS No.	502612-42-2
Molecular Formula	C9H12N2
Molecular Weight	148.21 g/mol
Synonyms	(5S)-5,6,7,8-Tetrahydroisoquinolin-5-amine; (5S)-5-Amino-5,6,7,8-tetrahydroisoquinoline; 5-Amino-5,6,7,8-tetrahydroisoquinoline (S-enantiomer); 5,6,7,8-Tetrahydroisoquinolin-5-amine, (5S)-; 502612-42-2; (S)-5,6,7,8-Tetrahydroisoquinolin-5-amine
EINECS	Contact for details

Quality Control

Our 5-Isoquinolinamine,5,6,7,8-Tetrahydro-,(5S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.