Description

Dimethyl (Tributylphosphoranylidene) Malonate is a specialized organophosphorus reagent widely used in organic synthesis. This compound matters for its critical role as a key intermediate in the Wittig-Horner reaction, enabling the efficient synthesis of α,β-unsaturated esters and other complex molecules. It is needed by research and development laboratories, pharmaceutical manufacturers, and fine chemical producers for constructing carbon-carbon double bonds with high stereoselectivity and yield.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for constructing olefinic linkages in active pharmaceutical ingredients (APIs) and drug candidates.
• Fine Chemical Production: Used in the synthesis of complex esters, fragrances, and specialty agrochemicals.
• Academic & Industrial Research: Serves as a versatile Horner-Wadsworth-Emmons (HWE) reagent for exploring new synthetic methodologies and material precursors.
• Polymer Chemistry: Employed in the preparation of monomers and functional polymers requiring specific alkene functionalities.
• Material Science: Acts as a building block for organic electronic materials and liquid crystals.

Basic Information

Product Name	Dimethyl (Tributylphosphoranylidene) Malonate
CAS No.	501939-32-8
Molecular Formula	C15H29O4P
Molecular Weight	304.36 g/mol
Synonyms	Dimethyl (tributylphosphoranylidene)malonate; Tributylphosphoranylidene Malonic Acid Dimethyl Ester; (Tributylphosphoranylidene)malonic Acid Dimethyl Ester; Dimethyl 2-(Tributylphosphoranylidene)malonate; HWE Reagent for Malonate; Wittig-Horner Reagent for Malonate Ester
EINECS	Contact for details

Quality Control

Our Dimethyl (Tributylphosphoranylidene) Malonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards required by the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.