Description

1,2-Indolizinediol, 1,2,3,5,8,8A-Hexahydro-, (1S,2S,8Ar)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its unique fused bicyclic diol structure makes it a valuable precursor for constructing complex molecules with precise three-dimensional architecture. This compound is primarily sought after by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands and organocatalysts.
• Fine Chemical Production: Employed in the multistep synthesis of complex natural product analogs and other high-value specialty chemicals.
• Academic & Industrial R&D: A valuable tool for methodological studies in synthetic organic chemistry, enabling new routes to heterocyclic and polycyclic frameworks.

Basic Information

Product Name	1,2-Indolizinediol, 1,2,3,5,8,8A-Hexahydro-, (1S,2S,8Ar)- (9Ci)
CAS No.	501939-11-3
Molecular Formula	C8H12NO2
Molecular Weight	154.19 g/mol
Synonyms	(1S,2S,8aR)-1,2,3,5,8,8a-Hexahydroindolizine-1,2-diol; (1S,2S,8aR)-Octahydro-2H-indolizine-1,2-diol; cis-1,2,3,5,8,8a-Hexahydroindolizine-1,2-diol; Chiral Indolizinediol Derivative; Bicyclic Amino Diol Building Block
EINECS	Contact for details

Quality Control

Our production of 1,2-Indolizinediol, 1,2,3,5,8,8A-Hexahydro-, (1S,2S,8Ar)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chiral purity. All materials are characterized by advanced analytical techniques including HPLC, GC, NMR, and optical rotation measurement. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.