Description

3-Isoquinolinecarboxamide,1,2,3,4-Tetrahydro-n-Phenyl-,(3S)-(9Ci) is a high-purity chiral organic compound with the CAS number 501355-25-5. This molecule serves as a critical chiral building block and intermediate in advanced organic synthesis, offering precise stereochemical control for the development of complex target molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and process development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of potential therapeutic agents, particularly in central nervous system (CNS) and oncology drug candidates.
• Asymmetric Synthesis: Employed as a stereodefined precursor for constructing complex heterocyclic frameworks via catalytic or stoichiometric reactions.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore novel chemical space.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in methodological studies for developing new synthetic transformations involving isoquinoline derivatives.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method validation in analytical laboratories.

Basic Information

Product Name	3-Isoquinolinecarboxamide,1,2,3,4-Tetrahydro-n-Phenyl-,(3S)-(9Ci)
CAS No.	501355-25-5
Molecular Formula	C₁₆H₁₆N₂O
Molecular Weight	252.31 g/mol
Synonyms	(3S)-1,2,3,4-Tetrahydro-N-phenyl-3-isoquinolinecarboxamide; (S)-N-Phenyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamide; N-Phenyl-1,2,3,4-tetrahydro-(3S)-isoquinoline-3-carboxamide; (S)-N-Phenyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide; 1,2,3,4-Tetrahydro-N-phenyl-(3S)-isoquinoline-3-carboxamide; (3S)-Tetrahydro-N-phenylisoquinoline-3-carboxamide; 501355-25-5
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and MS to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) are available upon request, detailing all relevant specifications. We adhere to strict quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.