Description

4-(1H-Tetrazol-5-Yl)Benzyl Alcohol, 97% is a high-purity, functionalized benzyl alcohol derivative featuring a tetrazole heterocycle. This compound serves as a versatile and valuable pharmaceutical intermediate and organic synthesis building block, enabling the introduction of both a hydroxymethyl group and a tetrazole moiety into target molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of sartan-class drugs (e.g., angiotensin II receptor blockers) and other active pharmaceutical ingredients (APIs) requiring a tetrazole pharmacophore.
• Organic Synthesis Reagent: Serves as a versatile precursor for introducing functional groups via reactions of the benzyl alcohol (e.g., esterification, etherification) and the tetrazole ring (e.g., metal complexation, click chemistry).
• Agrochemical Research: Used in the discovery and development of novel herbicides, fungicides, and insecticides where the tetrazole group can modulate biological activity.
• Coordination Chemistry & Material Science: Acts as a ligand for metal-organic frameworks (MOFs) or catalysts due to the nitrogen-rich tetrazole ring's metal-binding properties.
• Peptidomimetics & Bioisosteres: The tetrazole ring is a common carboxylate bioisostere, making this compound useful in medicinal chemistry for designing peptide analogs and improving metabolic stability.

Basic Information

Product Name	4-(1H-Tetrazol-5-Yl)Benzyl Alcohol, 97%
CAS No.	501126-02-9
Molecular Formula	C8H8N4O
Molecular Weight	176.18 g/mol
Synonyms	5-(4-(Hydroxymethyl)phenyl)-1H-tetrazole; (4-(1H-Tetrazol-5-yl)phenyl)methanol; 4-(1H-Tetrazol-5-yl)benzenemethanol; 4-(Tetrazol-5-yl)benzyl Alcohol; 4-(1H-Tetrazol-5-yl)benzyl alcohol; Tetrazole-5-benzyl alcohol derivative; 5-(4-Hydroxymethylphenyl)tetrazole
EINECS	Contact for details

Quality Control

Our 4-(1H-Tetrazol-5-Yl)Benzyl Alcohol, 97% is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing specifications such as assay (HPLC), identity (IR, NMR), and impurity profiles. We support cGMP compliance for pharmaceutical applications and can provide documentation to meet relevant regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.