Description

2-Thiopheneaceticacid,α-Amino-α-Cyclopropyl-5-Ethyl-(9Ci) is a high-value, non-proteinogenic amino acid derivative featuring a thiophene ring system. This compound matters as a sophisticated chiral building block, enabling the synthesis of complex molecules with precise stereochemistry for advanced research and development. It is primarily needed by pharmaceutical and agrochemical R&D teams for applications in medicinal chemistry, particularly in the development of novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the creation of advanced crop protection chemicals and herbicides, leveraging its unique heterocyclic structure.
• Medicinal Chemistry Research: Serves as a critical scaffold in drug discovery programs for constructing compound libraries and probing structure-activity relationships (SAR).
• Peptidomimetics Development: Employed in the design and synthesis of peptide analogs and mimetics due to its amino acid-like structure with a cyclopropyl constraint.
• Chemical Biology Probes: Utilized as a building block for creating labeled compounds or probes to study biological pathways and mechanisms.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring complex, multi-functional molecular architectures.

Basic Information

Product Name	2-Thiopheneaceticacid,α-Amino-α-Cyclopropyl-5-Ethyl-(9Ci)
CAS No.	500756-64-9
Molecular Formula	C11H15NO2S
Molecular Weight	225.31 g/mol
Synonyms	α-Amino-α-cyclopropyl-5-ethyl-2-thiopheneacetic acid; 2-Thiopheneacetic acid, α-amino-α-cyclopropyl-5-ethyl-; 5-Ethyl-α-(aminocyclopropyl)thiophene-2-acetic acid; (α-Amino-α-cyclopropyl-5-ethyl-2-thienyl)acetic acid; 2-(α-Amino-α-cyclopropyl)-5-ethylthiophene-2-acetic acid; Cyclopropaneacetic acid, α-amino-5-ethyl-2-thienyl-; (9CI) Index name derivative.
EINECS	Contact for details

Quality Control

Our 2-Thiopheneaceticacid,α-Amino-α-Cyclopropyl-5-Ethyl-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.