Description

5-(2-Chlorophenyl)Thiophene-2-Carboxylic Acid is a high-purity organic building block of significant importance in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging the thiophene moiety for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials, including semiconductors and conductive polymers.
• Chemical Synthesis: A versatile reagent for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Ligand & Catalyst Development: Used to create specialized ligands for metal-catalyzed cross-coupling reactions.

Basic Information

Product Name	5-(2-Chlorophenyl)Thiophene-2-Carboxylic Acid
CAS No.	500604-91-1
Molecular Formula	C11H7ClO2S
Molecular Weight	238.69 g/mol
Synonyms	2-(2-Chlorophenyl)thiophene-5-carboxylic acid; 5-(2-Chlorophenyl)-2-thiophenecarboxylic acid; 2-Chlorophenyl-5-thiophenecarboxylic acid; 5-(o-Chlorophenyl)thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 5-(2-chlorophenyl)-; 500604-91-1; 5-(2-Chlorophenyl)-2-thiophenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(2-Chlorophenyl)Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single impurity	≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.