Description

Ethyl 2-(2-Chlorophenyl)-2,3-Dihydro-Indole-3-Carboxylate is a high-purity, synthetically valuable indole derivative, serving as a critical advanced intermediate in modern pharmaceutical and agrochemical research. Its core value lies in providing a versatile, functionalized scaffold for constructing complex nitrogen-containing heterocycles, enabling the development of novel active ingredients. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality building blocks for synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex indole-based molecular libraries for high-throughput screening.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers and advanced organic materials.
• Process Chemistry & Scale-Up: Serves as a validated intermediate for optimizing synthetic routes and scaling up production of target molecules.

Basic Information

Product Name	Ethyl 2-(2-Chlorophenyl)-2,3-Dihydro-Indole-3-Carboxylate
CAS No.	500592-32-5
Molecular Formula	C17H16ClNO2
Molecular Weight	301.77 g/mol
Synonyms	Ethyl 2-(2-chlorophenyl)-2,3-dihydro-1H-indole-3-carboxylate; 2,3-Dihydro-2-(2-chlorophenyl)-1H-indole-3-carboxylic Acid Ethyl Ester; 3-Carbethoxy-2-(2-chlorophenyl)indoline; 1H-Indole-3-carboxylic acid, 2,3-dihydro-2-(2-chlorophenyl)-, ethyl ester; Ethyl 2-(o-chlorophenyl)indoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(2-Chlorophenyl)-2,3-Dihydro-Indole-3-Carboxylate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent lot-to-lot quality. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.