Description

[3-Amino-6-(3,4-Dimethoxyphenyl)Thieno[2,3-B]Pyridin-2-Yl](Phenyl)Methanone is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthesizing complex molecules for biological screening and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its unique thienopyridine scaffold.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study biological pathways and protein interactions.
• High-Value Fine Chemical Synthesis: Employed in multi-step synthetic routes requiring precise, high-purity intermediates for complex molecule assembly.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	[3-Amino-6-(3,4-Dimethoxyphenyl)Thieno[2,3-B]Pyridin-2-Yl](Phenyl)Methanone
CAS No.	500277-16-7
Molecular Formula	C22H18N2O3S
Molecular Weight	390.45 g/mol
Synonyms	(3-Amino-6-(3,4-dimethoxyphenyl)thieno[2,3-b]pyridin-2-yl)(phenyl)methanone; Phenyl[3-amino-6-(3,4-dimethoxyphenyl)thieno[2,3-b]pyridin-2-yl]methanone; 3-Amino-6-(3,4-dimethoxyphenyl)-2-benzoylthieno[2,3-b]pyridine; 2-Benzoyl-3-amino-6-(3,4-dimethoxyphenyl)thieno[2,3-b]pyridine; Thieno[2,3-b]pyridine derivative CAS 500277-16-7
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.