Description

3-(2,3-Dihydro-1H-Indol-1-Yl)-1-(4-Fluorophenyl)Pyrrolidine-2,5-Dione is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrrolidine-2,5-dione (succinimide) core substituted with indoline and fluorophenyl moieties. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel bioactive molecules targeting the central nervous system. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in neurological and psychiatric disorder research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• API Development: Serves as a precursor in the development of Active Pharmaceutical Ingredients (APIs) with modulatory activity on specific biological targets.
• Biochemical Tool Compound: Utilized in vitro and in vivo studies to investigate biological pathways and validate new therapeutic targets.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and pharmacology.

Basic Information

Product Name	3-(2,3-Dihydro-1H-Indol-1-Yl)-1-(4-Fluorophenyl)Pyrrolidine-2,5-Dione
CAS No.	500197-66-0
Molecular Formula	C18H15FN2O2
Molecular Weight	310.32 g/mol
Synonyms	1-(4-Fluorophenyl)-3-(2,3-dihydro-1H-indol-1-yl)pyrrolidine-2,5-dione; 3-(Indolin-1-yl)-1-(4-fluorophenyl)pyrrolidine-2,5-dione; N-(4-Fluorophenyl)-3-(indolin-1-yl)succinimide; Succinimide, 3-(2,3-dihydro-1H-indol-1-yl)-1-(4-fluorophenyl)-; 500197-66-0; FC-1078; AS-200 (Potential research code)
EINECS	Contact for details

Quality Control

Our 3-(2,3-Dihydro-1H-Indol-1-Yl)-1-(4-Fluorophenyl)Pyrrolidine-2,5-Dione is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.