Description

(5Z)-3-(2-Ethoxyphenyl)-5-(4-Fluorobenzylidene)-2-Thioxo-1,3-Thiazolidin-4-One CAS NO 500104-42-7 is a high-purity, synthetic heterocyclic compound belonging to the thiazolidinone class, characterized by its specific (5Z) stereochemistry. This compound serves as a critical advanced pharmaceutical intermediate and a versatile scaffold in medicinal chemistry research. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents, particularly for applications in oncology and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Biochemical Probe Development: Serves as a starting material for creating tool compounds to study specific enzyme or receptor interactions in biological systems.
• Organic Synthesis: Utilized in advanced organic synthesis for constructing complex molecules with potential biological significance.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Product Name	(5Z)-3-(2-Ethoxyphenyl)-5-(4-Fluorobenzylidene)-2-Thioxo-1,3-Thiazolidin-4-One
CAS No.	500104-42-7
Molecular Formula	C18H14FNO2S2
Molecular Weight	359.44 g/mol
Synonyms	5-(4-Fluorobenzylidene)-3-(2-ethoxyphenyl)-2-thioxo-1,3-thiazolidin-4-one; (5Z)-5-[(4-Fluorophenyl)methylene]-3-(2-ethoxyphenyl)-2-thioxo-4-thiazolidinone; 4-Thiazolidinone, 5-[(4-fluorophenyl)methylene]-3-(2-ethoxyphenyl)-2-thioxo-, (5Z)-; 500104-42-7; Thiazolidinone derivative 500104-42-7; (Z)-5-(4-Fluorobenzylidene)-3-(2-ethoxyphenyl)-2-thioxothiazolidin-4-one
EINECS	Contact for details

Quality Control

Our (5Z)-3-(2-Ethoxyphenyl)-5-(4-Fluorobenzylidene)-2-Thioxo-1,3-Thiazolidin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.