Description

2-Mercapto-3-p-Tolyl-5,6,7,8-Tetrahydro-3H-Benzo[4,5]Thieno[2,3-D]Pyrimidin-4-One is a high-purity, complex heterocyclic compound that serves as a critical advanced intermediate in pharmaceutical research and development. Its unique fused ring structure containing sulfur and nitrogen atoms makes it a valuable scaffold for synthesizing novel active pharmaceutical ingredients (APIs). This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Chemical Biology Probe: Serves as a scaffold or precursor in the design of molecular probes for studying enzyme mechanisms and biological pathways.
• Material Science Precursor: Potential intermediate in the synthesis of organic electronic materials or ligands for catalytic systems due to its electron-rich structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	2-Mercapto-3-p-Tolyl-5,6,7,8-Tetrahydro-3H-Benzo[4,5]Thieno[2,3-D]Pyrimidin-4-One
CAS No.	59898-69-0
Molecular Formula	C19H18N2OS2
Molecular Weight	354.49 g/mol
Synonyms	2-Mercapto-3-(4-methylphenyl)-5,6,7,8-tetrahydro-4H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one; 3-p-Tolyl-2-mercapto-5,6,7,8-tetrahydro-4H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one; 4H-Benzo[4,5]thieno[2,3-d]pyrimidin-4-one, 5,6,7,8-tetrahydro-2-mercapto-3-(4-methylphenyl)-; 59898-69-0; Benzo[4,5]thieno[2,3-d]pyrimidine derivative
EINECS	Contact for details

Quality Control

Our 2-Mercapto-3-p-Tolyl-5,6,7,8-Tetrahydro-3H-Benzo[4,5]Thieno[2,3-D]Pyrimidin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) in a sealed container. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.