Description

1,3-Dihydroisobenzofuran-1β-Ol is a specialized organic compound belonging to the isobenzofuran class, serving as a versatile chiral building block and intermediate in advanced chemical synthesis. Its unique fused bicyclic structure with a hydroxyl group makes it valuable for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and cardiovascular drug discovery.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its structural motif contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of functional organic materials, including polymers and liquid crystals.
• Fine Chemical Production: Acts as a building block for various specialty and performance chemicals.

Basic Information

Product Name	1,3-Dihydroisobenzofuran-1β-Ol
CAS No.	59868-79-0
Molecular Formula	C8H8O2
Molecular Weight	136.15 g/mol
Synonyms	1,3-Dihydroisobenzofuran-1-ol; 1-Hydroxy-1,3-dihydroisobenzofuran; 1,3-Dihydro-1-hydroxyisobenzofuran; Isochroman-1-ol; 1-Isochranol; (1R)-1,3-Dihydroisobenzofuran-1-ol (for enantiopure form); 1,3-Dihydro-2-benzofuran-1-ol
EINECS	Contact for details

Quality Control

Our 1,3-Dihydroisobenzofuran-1β-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and chiral purity verification where applicable, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiopure grade)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.