Description

5-Cyanothiophene-2-Carboxylic Acid is a versatile heterocyclic building block featuring both a carboxylic acid and a nitrile functional group on a thiophene core. This bifunctional nature makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is particularly valuable for pharmaceutical chemists and agrochemical researchers developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, including herbicides and fungicides.
• Material Science Precursor: Serves as a monomer or building block for conductive polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the synthesis of novel chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Synthesis: A versatile starting material for creating dyes, pigments, and other specialty chemicals.

Basic Information

Product Name	5-Cyanothiophene-2-Carboxylic Acid
CAS No.	59786-39-9
Molecular Formula	C6H3NO2S
Molecular Weight	153.16 g/mol
Synonyms	2-Thiophenecarboxylic acid, 5-cyano-; 5-Cyano-2-thiophenecarboxylic acid; 2-Carboxy-5-cyanothiophene; Thiophene-2-carboxylic acid, 5-cyano-; 5-Cyanothiophene-2-carboxylic acid; 5-Cyano-2-thiophene carboxylic acid; 5-Cyanothiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Cyanothiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.