Description

Hexamethylphosphorous Triamide (CAS NO 59758-27-9) is a versatile organophosphorus compound primarily valued as a highly effective reducing agent and ligand in complex chemical syntheses. Its significance lies in its ability to facilitate challenging transformations, particularly in the production of pharmaceuticals and advanced materials. This chemical is essential for research laboratories and industrial manufacturers engaged in fine chemical synthesis, catalyst development, and the creation of novel polymeric materials.

Application

• Pharmaceutical Intermediate Synthesis: Acts as a key reagent in the production of active pharmaceutical ingredients (APIs), especially for reduction and coupling reactions.
• Catalyst and Ligand in Organometallic Chemistry: Serves as a strong electron-donating ligand for transition metal catalysts used in polymerization and cross-coupling reactions.
• Polymer Industry: Utilized as a stabilizer and modifying agent in the synthesis of specialty polymers and resins to enhance specific material properties.
• Agricultural Chemical Production: Employed in the synthesis of certain pesticides and plant growth regulators where precise phosphorus chemistry is required.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and developing novel organophosphorus compounds.
• Fine Chemical Manufacturing: Used in the multi-step synthesis of complex, high-value organic molecules for electronics and other advanced applications.

Basic Information

Product Name	Hexamethylphosphorous Triamide
CAS No.	59758-27-9
Molecular Formula	C6H18N3P
Molecular Weight	163.20 g/mol
Synonyms	Hexamethylphosphorous Triamide; Tris(dimethylamino)phosphine; Phosphorous Tris(dimethylamide); P(NMe2)3; HMPT; Tris(N,N-dimethylamino)phosphine; Hexamethylphosphoramide (Note: This is a common misnomer, HMPA is the oxide); Tris(dimethylamino)phosphorus
EINECS	Contact for details

Quality Control

Our Hexamethylphosphorous Triamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We adhere to current Good Manufacturing Practices (cGMP) where applicable, and our quality system is designed to meet the stringent requirements of the pharmaceutical and fine chemical industries. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee supply reliability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~0.85 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.