Description

2-(5-Mercapto-4-Methyl-4H-1,2,4-Triazol-3-Yl)Acetonitrile is a versatile heterocyclic building block featuring a reactive nitrile group and a thiol functionality. This compound is highly valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is essential for chemists and manufacturers developing active ingredients, ligands, and advanced materials who require a reliable source of high-purity chemical intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those with triazole-based pharmacophores for antiviral, antifungal, or anticancer activity.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where the triazole ring system imparts biological activity.
• Ligand and Chelating Agent: Serves as a building block for creating specialized ligands in coordination chemistry and catalysis due to its mercapto and nitrogen donor sites.
• Material Science Research: Employed in the development of functional polymers, metal-organic frameworks (MOFs), and other advanced materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Custom Synthesis and R&D: A fundamental starting material for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	2-(5-Mercapto-4-Methyl-4H-1,2,4-Triazol-3-Yl)Acetonitrile
CAS No.	59682-60-9
Molecular Formula	C5H6N4S
Molecular Weight	154.19 g/mol
Synonyms	3-(Cyanomethyl)-4-methyl-4H-1,2,4-triazole-5-thiol; 2-(5-Mercapto-4-methyl-1,2,4-triazol-3-yl)acetonitrile; 4-Methyl-3-(cyanomethyl)-1,2,4-triazole-5-thiol; 5-Mercapto-4-methyl-4H-1,2,4-triazole-3-acetonitrile; (5-Mercapto-4-methyl-4H-1,2,4-triazol-3-yl)acetonitrile; 3-Cyanomethyl-4-methyl-1,2,4-triazole-5-thiol
EINECS	Contact for details

Quality Control

Our production of 2-(5-Mercapto-4-Methyl-4H-1,2,4-Triazol-3-Yl)Acetonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity suitable for research and industrial synthesis. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle and store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the original container. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.