Description

Trimethylammonium Phosphate Buffer is a high-purity, specialized buffer solution essential for maintaining precise pH control in sensitive biochemical and analytical processes. Its primary value lies in providing exceptional stability and reproducibility for applications where consistent ionic strength and pH are critical. This product is particularly vital for researchers and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic industries.

Application

• Biochemical Research & Assay Development: Used as a critical component in enzyme kinetics studies, protein purification, and cell culture media preparation.
• Pharmaceutical Analysis: Serves as a mobile phase modifier or diluent in High-Performance Liquid Chromatography (HPLC) and Capillary Electrophoresis (CE) for drug substance and product analysis.
• Molecular Biology: Provides a stable environment for nucleic acid hybridization, PCR, and other enzymatic reactions like DNA sequencing.
• Diagnostic Reagent Formulation: An integral buffer in the manufacture of clinical diagnostic kits and reagents to ensure test accuracy and shelf-life.
• Protein Crystallography: Employed in crystallizing proteins and other biological macromolecules to maintain optimal pH conditions.
• Electrophoresis: Used in techniques such as SDS-PAGE and isoelectric focusing (IEF) to maintain consistent pH gradients and ionic strength.

Basic Information

Product Name	Trimethylammonium Phosphate Buffer
CAS No.	59620-11-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Trimethylammonium Phosphate; Trimethylammonium Dihydrogen Phosphate; Tris(trimethylammonium) Phosphate; TMA Phosphate Buffer; Trimethylammonium Phosphate Solution; Phosphoric Acid, Tris(trimethylammonium) Salt; N,N,N-Trimethylmethanaminium Phosphate
EINECS	Contact for details

Quality Control

Our Trimethylammonium Phosphate Buffer is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets stringent specifications for pH, concentration, clarity, and absence of critical impurities. Certificates of Analysis (COA) documenting full test results are provided to guarantee traceability, consistency, and compliance with your application requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C). Do not freeze. Keep the container tightly sealed when not in use to prevent evaporation or contamination.

Specification

Item	Specification
Appearance	Clear, colorless solution
Identification (IR)	Conforms
pH (at 25°C)	As specified (e.g., 7.0 ± 0.1)
Assay (HPLC)	≥ 98.0%
Conductivity	Within specified range
Absorbance (UV)	Meets acceptance criteria
Bioburden	< 10 CFU/mL (for sterile grades)
Endotoxin	< 0.25 EU/mL (for parenteral grades)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.