Description

7-Methyl-5-Oxo-2-Phenyl-3,5-Dihydro-Indolizine-6-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique indolizine core structure. This compound is of significant value for its role as a critical building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis.
• Agrochemical Development: Used in the research and production of novel active ingredients for crop protection.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic & Institutional R&D: Utilized in universities and research institutes for exploring new chemical reactions and heterocyclic chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and development projects.

Basic Information

Product Name	7-Methyl-5-Oxo-2-Phenyl-3,5-Dihydro-Indolizine-6-Carbonitrile
CAS No.	59615-75-7
Molecular Formula	C16H12N2O
Molecular Weight	248.28 g/mol
Synonyms	6-Cyano-7-methyl-2-phenyl-3,5-dihydroindolizin-5-one; 7-Methyl-5-oxo-2-phenyl-3,5-dihydroindolizine-6-carbonitrile; 2-Phenyl-7-methyl-5-oxo-3,5-dihydroindolizine-6-carbonitrile; 6-Cyano-7-methyl-2-phenylindolizin-5(3H)-one; Indolizine-6-carbonitrile, 3,5-dihydro-7-methyl-5-oxo-2-phenyl-; (CAS 59615-75-7)
EINECS	Contact for details

Quality Control

Our 7-Methyl-5-Oxo-2-Phenyl-3,5-Dihydro-Indolizine-6-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.