Description

4-Chlorothiophene-2-Carboxylic Acid is a versatile heterocyclic building block characterized by its reactive carboxylic acid and chloro-substituted thiophene ring. This compound matters as a critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily needed by pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antiviral, anti-inflammatory, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging the thiophene scaffold for bioactivity.
• Material Science Precursor: Serves as a monomer or building block for conductive polymers, organic semiconductors, and liquid crystals.
• Organic Synthesis Reagent: Employed in coupling reactions (e.g., Suzuki, Sonogashira) and as a starting material for further functionalization to create diverse thiophene derivatives.
• Chemical Research & Development: Essential for academic and industrial R&D focused on heterocyclic chemistry and the exploration of new chemical entities.

Basic Information

Product Name	4-Chlorothiophene-2-Carboxylic Acid
CAS No.	59614-95-8
Molecular Formula	C5H3ClO2S
Molecular Weight	162.59 g/mol
Synonyms	2-Thiophenecarboxylic acid, 4-chloro-; 4-Chloro-2-thiophenecarboxylic acid; 4-Chloro-2-carboxythiophene; 4-Chlorothiophene-2-carboxylic acid; 4-Chlorothiophene-2-carboxylate; 4-Chloro-2-thiophenecarboxylate; 4-Chloro-2-thienoic acid; 4-Chlorothiophene-2-carboxylic acid (CAS 59614-95-8)
EINECS	Contact for details

Quality Control

Our 4-Chlorothiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.