Description

Climazolam CAS NO 59467-77-5 is a high-purity benzodiazepine derivative, recognized for its specific pharmacological research applications. This compound is critical for advancing studies in neurochemistry and the development of analytical reference standards. It is primarily utilized by pharmaceutical R&D laboratories, forensic science institutions, and academic research centers focused on central nervous system (CNS) activity.

Application

• Pharmacological Research: Used as a reference standard in studies investigating benzodiazepine receptor binding and activity.
• Analytical Chemistry: Serves as a high-purity certified reference material (CRM) for method development and validation in HPLC, GC-MS, and LC-MS systems.
• Forensic Analysis: Employed as a calibrant and control substance in toxicological screenings and substance identification protocols.
• Pharmaceutical Development: Acts as a key intermediate or active pharmaceutical ingredient (API) precursor in specialized synthetic pathways.
• Academic Studies: Utilized in university and institutional research for teaching and investigating the structure-activity relationships of psychoactive substances.

Basic Information

Product Name	Climazolam
CAS No.	59467-77-5
Molecular Formula	C19H18ClN3O
Molecular Weight	339.82 g/mol
Synonyms	Climazolam; 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine; SH-I-048A; SHI-048; 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-4-one; Imidazo-benzodiazepinone derivative
EINECS	Contact for details

Quality Control

Our Climazolam is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and residual solvent analysis by GC, to ensure it meets the stringent requirements for research-grade materials. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.