Description

Nikkomycin Z CAS NO 59456-70-1 is a potent nucleoside-peptide antibiotic belonging to the nikkomycin family, which acts as a competitive inhibitor of chitin synthase. This compound is of significant value in biochemical and pharmaceutical research for its targeted antifungal and insecticidal activity. It is primarily needed by researchers in the life sciences, agrochemical development, and pharmaceutical industries for studying fungal cell wall biosynthesis and developing novel therapeutic and crop protection agents.

Application

• Biochemical Research: Used as a specific tool compound to study the mechanism of chitin synthase and fungal cell wall formation.
• Antifungal Agent Development: Serves as a lead structure or reference standard in the discovery and development of new antifungal pharmaceuticals.
• Agricultural Research: Investigated for its potential as a bio-rational pesticide targeting chitin-containing pests like insects and pathogenic fungi.
• Microbiology Studies: Employed in in vitro assays to determine the susceptibility of various fungal strains.
• Enzyme Inhibition Studies: Utilized in enzymatic assays to characterize chitin synthase inhibition kinetics.
• Pharmaceutical Intermediates: Can act as a key intermediate or building block in the synthesis of more complex therapeutic agents.

Basic Information

Product Name	Nikkomycin Z
CAS No.	59456-70-1
Molecular Formula	C20H25N5O10
Molecular Weight	495.44 g/mol
Synonyms	Nikkomycin Z; Antibiotic Z 444; Nikkomycin Z (Antibiotic); L-4-(5-Amino-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-1-yl)-2,3,4-trideoxy-2-(formylamino)-D-erythro-hex-2-enonic acid 6-[3-(3-hydroxypyridin-4-yl)-2-methyl-1-oxo-2-propen-1-yl]amino-6-deoxy-α-D-glucopyranosyl ester; (2S,3S,4R,5R,6R)-5-[(E)-3-[(3-Hydroxy-4-pyridinyl)-2-methyl-1-oxo-2-propen-1-yl]amino]-6-[[(2S,3S,4R,5R)-5-(4-amino-2,6-dioxo-1,2,3,6-tetrahydro-1-pyrimidinyl)-3,4-dihydroxyoxolan-2-yl]methoxy]-3,4-dihydroxyoxane-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our Nikkomycin Z is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research-grade biochemicals, ensuring reliable and reproducible results for our clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants and an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Microbial Limits	To meet research-grade requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.