Description

1-Methoxy-3-Trimethylsiloxy-1,3-Butadiene is a specialized, high-value silyl enol ether derivative, serving as a versatile and reactive building block in advanced organic synthesis. Its core value lies in enabling efficient carbon-carbon bond formation, particularly in the synthesis of complex carbonyl compounds and heterocycles under mild conditions. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable synthetic intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for constructing complex molecular scaffolds via Michael additions and cycloaddition reactions.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific carbonyl functionalities.
• Fine Chemical Production: Employed in the manufacture of flavors, fragrances, and specialty chemicals where controlled reactivity is paramount.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, including annulation and tandem reaction sequences.
• Polymer & Material Science: Potential monomer or modifier for creating novel polymers with specific thermal or mechanical properties.

Basic Information

Item	Details
Product Name	1-Methoxy-3-Trimethylsiloxy-1,3-Butadiene
CAS No.	59414-23-2
Molecular Formula	C8H16O2Si
Molecular Weight	172.30 g/mol
Synonyms	1-Methoxy-3-(trimethylsilyloxy)-1,3-butadiene; 3-Trimethylsiloxy-1-methoxy-1,3-butadiene; Danishefsky's Diene; (1-Methoxy-3-trimethylsiloxy-1,3-butadiene); 1-Methoxy-3-(trimethylsiloxy)buta-1,3-diene; TMS enol ether of 1-Methoxy-1,3-butadien-3-ol
EINECS	Contact for details

Quality Control

Our 1-Methoxy-3-Trimethylsiloxy-1,3-Butadiene is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to verify identity, potency, and moisture content. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a recommended temperature of 2°C to 8°C. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.