Description

2-Fluoro-5-Iodobenzotrifluoride is a versatile and highly functionalized aromatic building block, prized for its unique combination of halogen substituents. This compound is critical for facilitating advanced cross-coupling reactions and introducing specific functionalities into complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic cores for bioactivity or further functionalization.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the iodine and fluorine atoms are leveraged for their electronic and metabolic stability properties.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings, enabling rapid diversification of chemical libraries.
• Fluorine Chemistry Studies: Used as a model compound in research focused on the effects of fluorine substitution on aromatic system reactivity and physical properties.
• Ligand and Catalyst Development: Employed in the synthesis of complex ligands for catalysis or as a scaffold for creating novel organocatalysts.

Basic Information

Product Name	2-Fluoro-5-Iodobenzotrifluoride
CAS No.	59382-39-7
Molecular Formula	C7H3F4I
Molecular Weight	289.99 g/mol
Synonyms	1-Fluoro-4-iodo-2-(trifluoromethyl)benzene; 2-Fluoro-α,α,α-trifluoro-5-iodotoluene; 5-Iodo-2-fluorobenzotrifluoride; 2-Fluoro-5-iodobenzotrifluoride; 2-Fluoro-5-iodo-α,α,α-trifluorotoluene; 2-Fluoro-5-iodo-(trifluoromethyl)benzene; Benzene, 1-fluoro-4-iodo-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Iodobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.