Description

3-(Aminosulfonyl)Thiophene-2-Carboxylic Acid is a high-purity, multifunctional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a carboxylic acid group and an aminosulfonyl moiety on a thiophene ring, enabling diverse chemical transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a crucial building block in the creation of novel herbicides, fungicides, and insecticides, leveraging its bioactive thiophene core.
• Material Science Research: Used in the synthesis of specialized polymers, ligands, and functional materials where the thiophene sulfonamide motif imparts specific electronic or binding properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and advanced intermediates under cGMP conditions.

Basic Information

Product Name	3-(Aminosulfonyl)Thiophene-2-Carboxylic Acid
CAS No.	59337-97-2
Molecular Formula	C5H5NO4S2
Molecular Weight	207.23 g/mol
Synonyms	2-Carboxy-3-sulfamoylthiophene; 3-Sulfamoyl-2-thiophenecarboxylic Acid; 2-Thiophenecarboxylic acid, 3-(aminosulfonyl)-; Thiophene-2-carboxylic acid, 3-sulfamoyl-; 3-Sulfamoylthiophene-2-carboxylic acid; 3-(Sulfamoyl)thiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-(Aminosulfonyl)Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment to ensure it meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.