Description

Methyl 3-Chlorosulfonylthiophene-2-Carboxylate is a high-value, multi-functional heterocyclic building block primarily used in advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals due to its reactive chlorosulfonyl and ester functional groups. It is specifically sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex thiophene-based molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require a thiophene core for enhanced activity.
• Material Science Research: Serves as a monomer or building block for developing conductive polymers, organic semiconductors, and advanced organic electronic materials.
• Dye and Pigment Industry: Employed in the synthesis of specialized heterocyclic dyes and pigments with unique color properties and stability.
• Custom Synthesis and Contract Manufacturing: An essential reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and Industrial R&D: A valuable tool for methodological chemistry research, including studies on sulfonylation reactions and heterocyclic chemistry.

Basic Information

Product Name	Methyl 3-Chlorosulfonylthiophene-2-Carboxylate
CAS No.	59337-92-7
Molecular Formula	C7H5ClO4S2
Molecular Weight	236.69 g/mol
Synonyms	3-(Chlorosulfonyl)thiophene-2-carboxylic acid methyl ester; Methyl 3-chlorosulfonyl-2-thiophenecarboxylate; 2-Thiophenecarboxylic acid, 3-(chlorosulfonyl)-, methyl ester; 3-Chlorosulfonylthiophene-2-carboxylic Acid Methyl Ester; Methyl 3-(chlorosulfonyl)thiophene-2-carboxylate; Thiophene-2-carboxylic acid, 3-(chlorosulfonyl)-, methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Chlorosulfonylthiophene-2-Carboxylate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed HPLC/GC purity, identity confirmation (IR, NMR), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.