Description

1-(4'-Methoxy)Phenyl-1,2,3,4-Tetrahydro-Isoquinoline is a versatile heterocyclic organic compound belonging to the tetrahydroisoquinoline class, a scaffold of significant pharmaceutical interest. This compound serves as a critical synthetic intermediate and building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material science sectors for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex molecules with potential biological activity, including central nervous system (CNS) agents and cardiovascular drugs.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing tetrahydroisoquinoline-based libraries for high-throughput screening and lead optimization.
• Agrochemical Research: Employed in the development of new pesticides and herbicides, leveraging its heterocyclic structure.
• Material Science: Investigated as a monomer or precursor for specialty polymers and advanced organic electronic materials.
• Academic & Contract Research: Serves as a standard or starting material in university laboratories and CROs (Contract Research Organizations) for methodological studies and custom synthesis projects.

Basic Information

Product Name	1-(4'-Methoxy)Phenyl-1,2,3,4-Tetrahydro-Isoquinoline
CAS No.	59224-74-7
Molecular Formula	C₁₆H₁₇NO
Molecular Weight	239.31 g/mol
Synonyms	1-(4-Methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline; 1-(p-Methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline; 4-Methoxy-N-(1,2,3,4-tetrahydroisoquinolin-1-yl)aniline; 1-(4-Methoxyphenyl)-3,4-dihydro-1H-isoquinoline; Tetrahydroisoquinoline, 1-(p-methoxyphenyl)-; 59224-74-7; 1-(4'-Methoxy)Phenyl-1,2,3,4-Tetrahydro-Isoquinoline
EINECS	Contact for details

Quality Control

Our 1-(4'-Methoxy)Phenyl-1,2,3,4-Tetrahydro-Isoquinoline is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system supports cGMP standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage under an inert atmosphere (nitrogen or argon), please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.