Description

3-Fluoro-D-[2-2H]Alanine Benzenesulphonate is a stable, deuterated and fluorinated amino acid derivative, specifically designed for advanced research and development applications. This compound is valued for its role as a sophisticated biochemical tool, offering unique isotopic and structural properties for mechanistic studies. It is primarily utilized by pharmaceutical researchers, analytical chemists, and academic institutions engaged in metabolic pathway analysis, tracer studies, and the development of novel diagnostic agents.

Application

• Pharmaceutical Research & Development: As a stable isotope-labeled precursor in the synthesis and metabolic studies of fluorinated drug candidates.
• Biochemical Tracer Studies: For investigating amino acid transport, metabolism, and protein synthesis mechanisms using mass spectrometry (MS) and nuclear magnetic resonance (NMR) techniques.
• Proteomics and Metabolomics: Serving as an internal standard or a probe in quantitative mass spectrometry for accurate biomarker analysis.
• Medical Imaging Agent Development: Potential use in the research of Positron Emission Tomography (PET) tracer precursors, leveraging the fluorine-18 analog.
• Enzyme Inhibition Studies: Acting as a substrate analog to study enzyme kinetics and inhibition, particularly for enzymes involved in amino acid metabolism.
• Academic Research: Fundamental research in organic chemistry, medicinal chemistry, and chemical biology exploring the properties of fluorinated and deuterated compounds.

Basic Information

Product Name	3-Fluoro-D-[2-2H]Alanine Benzenesulphonate
CAS No.	59189-07-0
Molecular Formula	C9H11D2FNO5S
Molecular Weight	267.27 g/mol
Synonyms	D-3-Fluoroalanine-2-d2 Benzenesulfonate; (2R)-2-Amino-3-fluoro-2,3,3-d3-propanoic acid benzenesulfonate; 3-Fluoro-D-alanine-2-d2 benzenesulfonic acid salt; Deuterated 3-Fluoro-D-alanine benzenesulfonate; Benzenesulfonic acid, compd. with (2R)-2-amino-3-fluoropropanoic acid-2-d2; 3-Fluoro-D-alanine-d2 benzenesulfonate; 3-F-D-Ala-2-d2 BSA
EINECS	Contact for details

Quality Control

Our 3-Fluoro-D-[2-2H]Alanine Benzenesulphonate is manufactured under strict quality control protocols to ensure high chemical purity and isotopic enrichment. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity (by HPLC), isotopic purity (deuterium content by MS or NMR), chiral purity, and identification. We adhere to cGMP principles where applicable to support its use in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Content)	≥ 98 atom % D (at designated position)
Chiral Purity (Chiral HPLC)	≥ 99.0% D-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.