Description

3-Fluoro-Dl-[2-2H]Alanine Benzenesulphonate is a deuterated and fluorinated alanine derivative, supplied as a benzenesulfonate salt. This compound is a critical building block in the synthesis of isotopically labeled molecules for advanced research and development. It is primarily utilized by pharmaceutical and biotechnology companies, as well as academic research institutions, for applications in metabolic studies, drug discovery, and the development of new analytical methods.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of deuterium-labeled drug candidates for pharmacokinetic (PK) and pharmacodynamic (PD) studies.
• Metabolic Pathway Analysis: Used as a tracer in mass spectrometry-based studies to investigate amino acid metabolism and related biochemical pathways.
• Proteomics and Biomarker Discovery: Serves as a stable isotope-labeled standard (SIL) for the accurate quantification of amino acids and peptides in complex biological samples.
• Medicinal Chemistry: Enables the introduction of both fluorine and deuterium atoms into target molecules to modulate their metabolic stability, bioavailability, and binding affinity.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Acts as a valuable probe in NMR studies due to the presence of deuterium and fluorine atoms, which do not interfere with 1H NMR signals.

Basic Information

Product Name	3-Fluoro-Dl-[2-2H]Alanine Benzenesulphonate
CAS No.	59189-04-7
Molecular Formula	C9H11D2FNO4S
Molecular Weight	251.27 g/mol
Synonyms	DL-3-Fluoro-[2-2H]alanine benzenesulfonate; 3-Fluoro-DL-alanine-2-d benzenesulfonate; (RS)-2-Amino-3-fluoro[2-2H]propanoic acid benzenesulfonate; 3-Fluoro-DL-alanine-2-d benzene sulfonic acid salt; 3-Fluoro-d1-DL-alanine benzenesulfonate; Benzenesulfonic acid, compd. with 2-amino-3-fluoro[2-2H]propanoic acid (1:1); 3-F-DL-Ala(2-d) benzenesulfonate
EINECS	Contact for details

Quality Control

Our 3-Fluoro-Dl-[2-2H]Alanine Benzenesulphonate is manufactured under strict quality control protocols to ensure high chemical purity and isotopic enrichment. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chemical purity (by HPLC), isotopic purity (deuterium content by NMR or MS), and identity confirmation. We adhere to cGMP principles where applicable to support our clients in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Content)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.