Description

4-(4-Bromophenyl)But-3-Yn-1-Ol is a versatile brominated aromatic alkyne derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its bifunctional molecular architecture, featuring both a terminal alkyne and a hydroxyl group, which enables precise and modular construction of complex molecules. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications in cross-coupling reactions, click chemistry, and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the creation of novel phosphine or N-heterocyclic carbene ligands for transition metal catalysis.
• Click Chemistry Substrate: The terminal alkyne group makes it an ideal participant in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer functionalization.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	4-(4-Bromophenyl)But-3-Yn-1-Ol
CAS No.	59099-79-5
Molecular Formula	C10H9BrO
Molecular Weight	225.08 g/mol
Synonyms	4-(4-Bromophenyl)-3-butyn-1-ol; 4-(p-Bromophenyl)-3-butyn-1-ol; 1-(4-Bromophenyl)-3-butyn-1-ol (tautomeric form); 4-Bromophenylbut-3-yn-1-ol; p-Bromophenyl propargyl carbinol; 4-(4-Bromophenyl)but-3-yn-1-ol; 59099-79-5
EINECS	Contact for details

Quality Control

Our 4-(4-Bromophenyl)But-3-Yn-1-Ol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), identity confirmation (by FT-IR and/or NMR), and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.