Description

4-Oxo-4-Thiophen-2-Yl-Butyric Acid Ethyl Ester is a high-purity organic building block and synthetic intermediate of significant commercial importance. Its core value lies in its versatile thiophene and keto-ester functionalities, which are critical for constructing complex molecular architectures in advanced chemical synthesis. This compound is primarily needed by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and material science industries for developing active ingredients and novel functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing thiophene heterocycles for various therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive carbonyl and ester groups.
• Material Science Research: Acts as a monomer or building block for developing organic semiconductors, conductive polymers, and other advanced functional materials.
• Organic Synthesis & Catalysis: Employed in academic and industrial research for constructing complex organic molecules, including natural product analogs and ligands for catalytic systems.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals, dyes, and pigments where the thiophene moiety is required.

Basic Information

Product Name	4-Oxo-4-Thiophen-2-Yl-Butyric Acid Ethyl Ester
CAS No.	59086-25-8
Molecular Formula	C10H12O3S
Molecular Weight	212.26 g/mol
Synonyms	Ethyl 4-oxo-4-(thiophen-2-yl)butanoate; 4-(2-Thienyl)-4-oxobutanoic Acid Ethyl Ester; 2-Thiopheneacetic acid, γ-oxo-, ethyl ester; Ethyl γ-oxo-2-thiophenebutyrate; 4-Oxo-4-(2-thienyl)butyric acid ethyl ester; Butanoic acid, 4-oxo-4-(2-thienyl)-, ethyl ester; 59086-25-8; 4-(Thiophen-2-yl)-4-oxobutyric acid ethyl ester
EINECS	Contact for details

Quality Control

Our 4-Oxo-4-Thiophen-2-Yl-Butyric Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.