Description

2-Bromo-3-Fluoronaphthalene is a halogenated naphthalene derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its precise molecular architecture, featuring both bromine and fluorine substituents on the naphthalene core, makes it a critical building block for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require specialized intermediates for drug discovery, ligand synthesis, and the development of functional organic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a backbone for creating sophisticated ligands used in transition metal catalysis and asymmetric synthesis.
• Organic Electronic Materials: Building block for n-type semiconductors, organic light-emitting diodes (OLEDs), and other electronic materials due to its electron-deficient aromatic system.
• Fluorine Chemistry Research: Valuable substrate for studying nucleophilic aromatic substitution (SNAr) and cross-coupling reactions involving halogenated arenes.
• Liquid Crystal and Dye Intermediates: Used in the synthesis of fluorinated dyes and liquid crystal compounds for display technologies.

Basic Information

Product Name	2-Bromo-3-Fluoronaphthalene
CAS No.	59024-94-1
Molecular Formula	C10H6BrF
Molecular Weight	225.06 g/mol
Synonyms	3-Fluoro-2-bromonaphthalene; 2-Bromo-3-fluoronaphthalene; Naphthalene, 2-bromo-3-fluoro-; 2-Brom-3-fluornaphthalin; 59024-94-1; 3-Fluoro-2-bromo-naphthalene
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Fluoronaphthalene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical characteristics. Our production adheres to cGMP principles where applicable, ensuring consistency and reliability for critical research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound should be handled under an inert atmosphere for long-term storage to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.