Description

1-Iodopropane-D7 is a deuterium-labeled isotopologue of 1-iodopropane, a valuable building block in synthetic organic chemistry and analytical research. Its core value lies in its utility as a stable, non-radioactive isotopic tracer, enabling precise mechanistic studies and quantitative analysis via mass spectrometry and NMR spectroscopy. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors, particularly for drug metabolism studies (DMPK), environmental fate tracking, and the development of novel deuterated active pharmaceutical ingredients (APIs).

Application

• Deuterated Internal Standards: Used as a quantitative standard in GC-MS and LC-MS for the accurate analysis of propyl-containing compounds in complex matrices.
• Pharmaceutical Research (DMPK): A critical tool for tracing metabolic pathways, studying bioavailability, and understanding the pharmacokinetics of new drug candidates.
• Synthetic Chemistry: Serves as a deuterium-labeled propylating agent for introducing the CD3CD2CD2- moiety into target molecules to alter physical and metabolic properties.
• Mechanistic Studies: Employed in isotopic labeling experiments to elucidate reaction mechanisms and kinetic isotope effects in organic transformations.
• Deuterated API Development: A key precursor in the synthesis of deuterated drugs, where the substitution of hydrogen with deuterium can improve metabolic stability and efficacy.
• NMR Spectroscopy: Used as a solvent or chemical shift reference, and for specialized NMR experiments due to its distinct spectroscopic signature.

Basic Information

Product Name	1-Iodopropane-D7
CAS No.	59012-23-6
Molecular Formula	C3D7I
Molecular Weight	198.00 g/mol (approx.)
Synonyms	Propyl-d7 Iodide; n-Propyl-d7 Iodide; 1-Iodo[1,1,2,2,3,3,3-D7]propane; Deuterated n-Propyl Iodide; [D7]-1-Iodopropane; Perdeuterated 1-Iodopropane; CD3CD2CD2I; 1-Iodopropane (D7)
EINECS	Contact for details

Quality Control

Our 1-Iodopropane-D7 is produced under strict quality management systems to ensure batch-to-batch consistency and high isotopic purity. Each lot undergoes comprehensive analysis, including NMR, GC-MS, and HPLC, to confirm chemical and isotopic purity, identity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications, including deuterium enrichment (Atom % D), are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. Due to its light-sensitive nature and organic solvent properties, handle and store with appropriate precautions to maintain stability and purity.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 99.0% (by NMR or MS)
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.