Description

(R)-Clorprenaline is a high-purity, single-enantiomer compound belonging to the class of β-2 adrenergic receptor agonists. This specific stereoisomer is of significant interest for its targeted pharmacological activity and serves as a critical chiral building block in advanced pharmaceutical synthesis. It is essential for research and development chemists and manufacturers in the pharmaceutical and fine chemical industries who require precise, enantiomerically pure intermediates for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of enantiomerically pure bronchodilators and other adrenergic drugs.
• Biochemical Research: Used as a reference standard and active compound in studies targeting β-2 adrenergic receptors to understand signaling pathways and drug-receptor interactions.
• Asymmetric Synthesis: Employed as a chiral precursor or resolving agent in the synthesis of complex, stereochemically defined molecules.
• Metabolite Studies: Utilized in the development and validation of analytical methods for pharmacokinetic and metabolic profiling studies.
• Process Chemistry Development: Serves as a model compound for optimizing chiral separation techniques, such as preparative HPLC or crystallization.

Basic Information

Product Name	(R)-Clorprenaline
CAS No.	58948-07-5
Molecular Formula	C11H16ClNO2
Molecular Weight	229.70 g/mol
Synonyms	(R)-1-(2-Chlorophenyl)-2-(isopropylamino)ethanol; (R)-Chlorprenaline; (R)-Isoprophenamine; (R)-2-Chloro-α-[(isopropylamino)methyl]benzyl alcohol; (R)-Clorprenaline hydrochloride (salt form); (-)-(R)-Clorprenaline; (R)-Benzylethanolamine derivative
EINECS	Contact for details

Quality Control

Our (R)-Clorprenaline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, identity confirmation by IR and NMR, and purity assessment. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.