Description

1,2,3,4-Tetrahydronorharmane Hydrochloride is a high-purity, heterocyclic organic compound in its hydrochloride salt form, valued for its role as a key synthetic intermediate and research chemical. Its structural framework makes it a valuable building block in medicinal chemistry and biochemical research. This product is essential for pharmaceutical R&D laboratories, academic institutions, and fine chemical manufacturers engaged in the synthesis of complex alkaloids and bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex alkaloids and potential therapeutic agents targeting neurological pathways.
• Biochemical Research: Used as a reference standard or tool compound in studies related to serotonin and monoamine oxidase (MAO) interactions.
• Medicinal Chemistry: Serves as a core scaffold for the development and structure-activity relationship (SAR) studies of novel pharmacologically active compounds.
• Academic Research: Employed in university and institutional labs for synthetic organic chemistry projects and the study of β-carboline derivatives.
• Fine Chemical Synthesis: Utilized as a specialized building block for creating custom, high-value chemical entities in contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Product Name	1,2,3,4-Tetrahydronorharmane Hydrochloride
CAS No.	58911-02-7
Molecular Formula	C₁₁H₁₃ClN₂
Molecular Weight	208.69 g/mol
Synonyms	1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole Hydrochloride; Norharmane Hydrochloride, Tetrahydro-; 9H-Pyrido[3,4-b]indole, 1,2,3,4-tetrahydro-, hydrochloride; Tetrahydro-β-carboline Hydrochloride; 1,2,3,4-Tetrahydro-norharman Hydrochloride; 1,2,3,4-Tetrahydro-β-carboline HCl; Norharman HCl, Tetrahydro-; 58911-02-7
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydronorharmane Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with data from HPLC, NMR, and mass spectrometry. While produced to meet high standards for research chemicals, specifications can be tailored to support specific project requirements in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.