Description

(17R)-4-[2-(Diethylamino)Ethyl]-4,21-Secoajmalan-17-Ol is a high-purity, semi-synthetic indole alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly those targeting neurological and cardiovascular systems. The compound is supplied with a Certificate of Analysis to ensure batch-to-batch consistency and reliability for sensitive applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathways for novel indole-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical labs.
• Biochemical Research: Employed in pharmacological studies to investigate structure-activity relationships (SAR) of alkaloid derivatives.
• Preclinical Development: Serves as a starting material or intermediate in the synthesis of candidate compounds for preclinical evaluation.
• Academic Research: Utilized in university and institutional labs for synthetic organic chemistry and medicinal chemistry projects.

Basic Information

Product Name	(17R)-4-[2-(Diethylamino)Ethyl]-4,21-Secoajmalan-17-Ol
CAS No.	58893-13-3
Molecular Formula	C24H38N2O2
Molecular Weight	386.58 g/mol
Synonyms	4-[2-(Diethylamino)ethyl]-4,21-secoajmalan-17-ol, (17R)-; 17-Hydroxy-4-[2-(diethylamino)ethyl]-4,21-secoajmalan; Secoajmalan derivative; Ajmaline derivative; Indole alkaloid intermediate; Rauwolfia alkaloid analog; Diethylaminoethyl-secoajmalol
EINECS	Contact for details

Quality Control

Our (17R)-4-[2-(Diethylamino)Ethyl]-4,21-Secoajmalan-17-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and oxidation, prolonged exposure to air or light should be avoided. Keep the container sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.