Description

Thiophene, 2-(3-Fluorophenyl)- is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role in modulating the electronic and steric properties of target molecules, enabling the development of novel materials and active pharmaceutical ingredients. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Organic Electronic Materials: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and asymmetric synthesis.
• Chemical Research: A versatile building block for academic and industrial research in medicinal chemistry and material science.
• Fluorine Chemistry Studies: Used as a model compound to study the effects of fluorine substitution on the reactivity of thiophene-based systems.

Basic Information

Product Name	Thiophene, 2-(3-Fluorophenyl)-
CAS No.	58861-49-7
Molecular Formula	C10H7FS
Molecular Weight	178.23 g/mol
Synonyms	2-(3-Fluorophenyl)thiophene; 3-Fluoro-2-thienylbenzene; 3-Fluorophenylthiophene; 2-(3-Fluorophenyl)thiophene; m-Fluorophenylthiophene; Thiophene, 2-(m-fluorophenyl)-; 1-Fluoro-3-(thiophen-2-yl)benzene; 3-(Thiophen-2-yl)fluorobenzene
EINECS	Contact for details

Quality Control

Our Thiophene, 2-(3-Fluorophenyl)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. For custom synthesis projects, we adhere to cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.