Description

(5Alpha,6Alpha)-4,5-Epoxy-6-Hydroxy-17-Methylmorphinan-3-Yl Acetate is a high-purity, synthetic opioid derivative of significant interest in advanced pharmaceutical research and development. Its primary value lies in its role as a critical pharmaceutical intermediate for the synthesis of specialized analgesic compounds and for metabolic studies. This compound is essential for research institutions, pharmaceutical manufacturers, and analytical laboratories engaged in neuropharmacology, drug discovery, and the development of controlled substance standards.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathway for potent analgesic and antitussive medications.
• Reference Standard: Used in analytical chemistry for method development, validation, and quality control testing of opioid-based pharmaceuticals.
• Metabolic Research: Serves as a substrate or standard in studies investigating the biotransformation and pharmacokinetics of morphinan derivatives.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to develop new therapeutic agents with modified efficacy and safety profiles.
• Forensic Analysis: Employed as a certified reference material for the identification and quantification of opioids in forensic toxicology.

Basic Information

Product Name	(5Alpha,6Alpha)-4,5-Epoxy-6-Hydroxy-17-Methylmorphinan-3-Yl Acetate
CAS No.	58752-60-6
Molecular Formula	C20H25NO4
Molecular Weight	343.42 g/mol
Synonyms	6-Hydroxy-4,5-epoxy-17-methylmorphinan-3-yl acetate; 6-Hydroxy-4,5α-epoxy-17-methylmorphinan-3α-yl acetate; 3-Acetoxy-4,5α-epoxy-6α-hydroxy-17-methylmorphinan; 6α-Hydroxy-4,5α-epoxy-17-methylmorphinan-3α-yl acetate; A derivative of Oxymorphone; 6-Hydroxyoxymorphone 3-acetate
EINECS	Contact for details

Quality Control

Our (5Alpha,6Alpha)-4,5-Epoxy-6-Hydroxy-17-Methylmorphinan-3-Yl Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity, the product should be stored under an inert atmosphere to prevent oxidation. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%
Assay	97.0% - 102.0% (on anhydrous basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.