Description

Ethylketocyclazocine is a potent and selective chemical compound belonging to the benzomorphan class of opioid receptor ligands. Its primary value lies in its utility as a critical reference standard and research chemical for pharmacological studies, particularly in the investigation of κ-opioid receptor (KOR) activity. This product is essential for pharmaceutical R&D laboratories, academic research institutions, and analytical facilities focused on neuroscience, pain management, and receptor biochemistry. Precise characterization of such compounds is fundamental for advancing the understanding of neurochemical pathways and developing novel therapeutic agents.

Application

• Pharmacological Research: Used as a reference standard in studies investigating the binding affinity and functional activity at κ-opioid receptors (KOR).
• Neuroscience Studies: A key tool for exploring the role of the κ-opioid system in pain perception, mood regulation, and addiction pathways.
• Analytical Method Development: Serves as a high-purity calibrant for developing and validating analytical methods such as HPLC, LC-MS, and GC-MS in bioanalytical laboratories.
• Drug Discovery & Development: Acts as a chemical scaffold or comparator in the discovery and structural optimization of new centrally-acting pharmaceutical agents.
• Quality Control & Assurance: Employed as an impurity reference or system suitability standard in the QC testing of related pharmaceutical compounds and APIs.
• Academic Teaching: Used in advanced university chemistry and pharmacology courses to demonstrate principles of receptor-ligand interaction and drug design.

Basic Information

Product Name	Ethylketocyclazocine
CAS No.	58640-84-9
Molecular Formula	C₁₉H₂₇NO
Molecular Weight	285.43 g/mol
Synonyms	EKC; Ethylketazocine; (±)-Ethylketocyclazocine; U-50488 (Note: U-50488 is a closely related but distinct compound; often confused); 2-(3,4-Dichlorophenyl)-N-methyl-N-[(1R,2R)-2-pyrrolidin-1-ylcyclohexyl]acetamide (Note: This is the structure of U-50488, provided for clarity and common search association); Benzomorphan derivative; Kappa opioid receptor agonist reference standard.
EINECS	Contact for details

Quality Control

Our Ethylketocyclazocine is produced and handled under strict quality management protocols to ensure identity, purity, and consistency for research applications. Each batch is subjected to comprehensive analytical testing, including chromatographic purity assays and spectroscopic identification. A Certificate of Analysis (COA) detailing batch-specific results is provided to guarantee compliance with your research specifications and to support regulatory documentation where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider keeping the product under inert atmosphere to maximize stability. Keep the container securely sealed in a dry environment to prevent any potential moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.