Description

1-(Piperidin-4-Yl)Indolin-2-One Hydrochloride is a high-purity pharmaceutical intermediate and research chemical, supplied as a stable hydrochloride salt. This compound is of significant value for its role as a key building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, especially within the fields of central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in API manufacturing.
• Academic & Institutional Research: Employed in biochemical and pharmacological studies to investigate receptor interactions and enzyme inhibition.
• Process Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.

Basic Information

Product Name	1-(Piperidin-4-Yl)Indolin-2-One Hydrochloride
CAS No.	58562-44-0
Molecular Formula	C13H17ClN2O
Molecular Weight	252.74 g/mol
Synonyms	1-(4-Piperidinyl)-2-indolinone hydrochloride; 2-Oxo-1-(4-piperidinyl)indoline hydrochloride; 1-(Piperidin-4-yl)indolin-2-one HCl; Indolin-2-one, 1-(4-piperidinyl)-, hydrochloride; 58562-44-0; 1-(4-Piperidyl)indolin-2-one hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Piperidin-4-Yl)Indolin-2-One Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.