Description

Saikosaponin B1 is a bioactive triterpenoid saponin primarily isolated from the roots of *Bupleurum* species, a key herb in traditional medicine. This high-purity reference standard is critical for pharmaceutical research and quality control, enabling precise analysis and development of new therapeutic agents. It is essential for laboratories and manufacturers in the pharmaceutical, nutraceutical, and herbal extract industries focused on standardization and bioactivity studies.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the identification and quantification of Saikosaponin B1 in raw materials and finished herbal products.
• Bioactivity Research: Serves as a key compound in pharmacological studies investigating anti-inflammatory, hepatoprotective, antiviral, and immunomodulatory effects.
• Herbal Extract Standardization: Critical for the quality control and standardization of *Bupleurum* (Chai Hu) extracts to ensure consistent potency and efficacy.
• Analytical Method Development: Employed in developing and validating analytical methods such as HPLC, UPLC, and LC-MS for saponin profiling.
• Nutraceutical Formulation: Incorporated into high-end dietary supplements where standardized bioactive components are required.
• Academic Research: Used in university and institutional research for studying the biochemistry and mechanism of action of triterpenoid saponins.

Basic Information

Product Name	Saikosaponin B1
CAS No.	58558-08-0
Molecular Formula	C42H68O13
Molecular Weight	780.98 g/mol
Synonyms	Saikosaponin B; Saikosaponin B-1; (3β,4α,16β)-13,28-Epoxy-16,23-dihydroxy-3-[(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]olean-11-en-29-oic acid γ-lactone; Chikusetsusaponin IVa; SS-B1
EINECS	Contact for details

Quality Control

Our Saikosaponin B1 is manufactured under strict quality management systems. Each batch undergoes rigorous identity, purity, and impurity profile testing via advanced chromatographic and spectroscopic methods to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and specifications are provided for every lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.